Intraoperative intact PTH assay is adjunct used in minimal invasive or focused parathyroid surgery. PTH is hormone secreted by the parathyroid gland and in hyperparathyroidism it is increased several folds in majority of our patients. Pre-requisite for minimal invasive or focussed parathyroid surgery is that the disease should be localized (i.e tumour should be picked up on pre-operative anatomical and functional imaging like Ultrasound, Sestamibi etc.) to one out of four parathyroid glands. Combined positive predictive value (i.e to detect the correct site of tumour) of these preoperative imaging modalities is more that 90% but there are cases which may be missed out. By adding intraoperative PTH assay we can further decrease the chance of missing those ectopic parathyroid tumour and similarly chances of surgical failure.
In this we take five PTH samples: Pre-incision, pre-excision of tumour, 5, 10, 15 minute post excision of tumour and usually more than 50 % drop in PTH level is reflective of surgical cure i.e the culprit gland has been taken out.
The thyroid is butterfly shaped gland situated in front of the neck around windpipe just below the voice box. It has two lobes right & left attached with isthmus….
Hypothyroidism is the condition in which thyroid gland does not produce enough hormones i.e T3, T4 to sustain our normal body functions Common symptoms that…
thyroid is a condition in which thyroid gland produce excess hormones i.e T3, T4 in contrary to the amount required by our body. Common symptoms that patients…
Goiter in simple words means swollen thyroid. The common perception among community is any thyroid related disorders means abnormal functional thyroid…..
Thyroid cancer is the commonest endocrine malignancy with more prevalence among women as compared to men.The number of patients with thyroid cancer….
Graves disease is a form of hyperthyroidism which is cause by generalized overactivity of thyroid gland. It is named after Robert Graves, an Irish physician, who first described this disorder…
Thyroid surgery has evolved over last few decades and have become much safer now in hands of experts. There are conditions when patient may need to undergo thyroid surgery……
Each individual has two voice nerves one on each side of wind pipe and behind the thyroid gland.These are recurrent laryngeal nerve (RLN) and external branch of superior……
Each individual has two voice nerves one on each side of wind pipe and behind the thyroid gland.These are recurrent laryngeal nerve (RLN) and external branch of superior laryngeal nerve (EBSLN). These nerves maintain tone, pitch…
