It is the syndrome associated with hypercortisolism. Cause can be from Pituitary, Adrenal, Exogenous (i.e external steroid intake) or from any cortisol secreting cancer. Symptoms may vary according to the site of production, however common symptoms include:
| Truncal obesity, rounded face | 90% |
| Hypertension | 75% |
| Facial pletharo | 75% |
| Hirsuitism, acne | 65% |
| Thin skin, easy bruising, striae | 65% |
| Proximal muscle weakness | 60% |
| Oligomenorrhea/amennorhea | 60% |
| Psychiatric disorder | 40% |
| Oedema | 40% |
| Osteoporosis | 40% |
Impaired blood glucose, loss of libido etc.
Screening test includes Screening test consists of 24 hr urinary free cortisol, Night time cortisol (Serum, salicary), Overnight low dose dexamethasone suppression test. Confirmatory test may include Low Dose Dexamethasone suppression test and ACTH.
Treatment options includes Adrenalectomy, Endoscopic Pituitary surgery or Removal of Extra-adrenal tumour.
The thyroid is butterfly shaped gland situated in front of the neck around windpipe just below the voice box. It has two lobes right & left attached with isthmus….
Hypothyroidism is the condition in which thyroid gland does not produce enough hormones i.e T3, T4 to sustain our normal body functions Common symptoms that…
thyroid is a condition in which thyroid gland produce excess hormones i.e T3, T4 in contrary to the amount required by our body. Common symptoms that patients…
Goiter in simple words means swollen thyroid. The common perception among community is any thyroid related disorders means abnormal functional thyroid…..
Thyroid cancer is the commonest endocrine malignancy with more prevalence among women as compared to men.The number of patients with thyroid cancer….
Graves disease is a form of hyperthyroidism which is cause by generalized overactivity of thyroid gland. It is named after Robert Graves, an Irish physician, who first described this disorder…
Thyroid surgery has evolved over last few decades and have become much safer now in hands of experts. There are conditions when patient may need to undergo thyroid surgery……
Each individual has two voice nerves one on each side of wind pipe and behind the thyroid gland.These are recurrent laryngeal nerve (RLN) and external branch of superior……
Each individual has two voice nerves one on each side of wind pipe and behind the thyroid gland.These are recurrent laryngeal nerve (RLN) and external branch of superior laryngeal nerve (EBSLN). These nerves maintain tone, pitch…
